Latency is bad
Is your buffer size set to 128 samples or less? Open up the I/O Window and pick the buffer size that works best on your system. We recommend a buffer size no more than 256 samples.
Close all unnecessary applications on your computer. Running several large applications can cause latency.
Ensure that you have the correct driver installed for your audio interface.
It might not be computational latency at all! Make sure that all of the dead-space is removed from the front of your samples. See trimming.